Day 2 :
California State Univeristy, USA
Time : 09:00-09:45
Loretta Graziano Breuning, PhD is Founder of the Inner Mammal Institute and author of Habits of a Happy Brain: Retrain your brain to boost your serotonin, dopamine, oxytocin and endorphin levels. She’s Professor Emerita of Management at California State University, East Bay. As a teacher and mom, she was not convinced by prevailing theories of human motivation. Then she learned about the brain chemistry we share with earlier mammals, and everything made sense. She created the Inner Mammal Institute to provide resources that help people manage their mammal brain. Her books have been translated into Spanish, Russian, Chinese, Arabic, French, and Turkish.
The brain chemicals that make us feel good are inherited from earlier mammals. They evolved to do a job, not to flow for no reason. They reward a mammal for behaviors that promote survival. But the mammal brain defines survival in a quirky way: it cares about the survival of your genes, and it relies on neural pathways built in youth. When you know why the mammal brain turns on dopamine, oxytocin, and serotonin, you can find healthy ways to stimulate them. Simple examples are provided. The goal is not endless ecstasy because the happy chemicals are not meant to be on all the time. They reset to neutral when their job is done and you have to do more to get more. The goal is tranquility and self-acceptance. Old ways of triggering these chemicals make sense
Quantum University, USA
Keynote: Life coaching and energy work facilitates the healing of women affected by narcissistic relationships
Time : 09:45-10:30
Bindu Babu is a Quantum-Based Transformational Life Coach who is an expert in her field in the healing and recovery from toxic narcissistic relationships. She uses the Quantum Medicinal healing approach in her sessions and programs. She is a well sought out Motivational Speaker where she has spoken at prestigious universities such as NYU & Harvard for the National Symposium on Personal Development. Dr Babu is a Medical Physician and has a Doctorate in Natural Medicine and a PhD in Integrative Medicine hence being trained in both allopathic and holistic modalities. She is a Certified Reiki Master and a Past Life Regression Therapist where she completed her professional training at the Weiss Institute with Dr Brian L Weiss MD author of "Many Lives and Many Masters". Dr Bindu Babu is the Professor of Holistic Entrepreneurship at Quantum University and has a well-established life coaching practice in New York City.
Introduction: We will look at the fundamental attributes of Quantum Medicinal Approach of Life Coaching and Energy work, its positive role in transformational healing and recovery of women who have been involved in narcissistic relationships. It will focus on women who have endured devastating emotional, physical and psychological consequences through these relationships, the different allopathic methods, both chemical and behavioral that has been applied and how the Quantum Medicinal approach had an effective role in their journey towards healing and recovery.
Methodology: This awareness comprises of five case studies of women, each with their own individualistic lifestyle, habits, goals, socioeconomic status and beliefs. These women all have been subjected to narcissistic partner abuse resulting in their self-worth, self-esteem, and total being left in shreds. According to these women, they are suffering from mental and physical aftermaths, and felt seeking recovery through allopathic modalities alone have not deemed effective in long-term results and permanence. These case studies have been based on the client feedback and the observational level of healing experience that is seen within one year of solid commitment & continuity towards Quantum-Based Life Coaching, Energy work and other Quantum modalities specifically, Meditation, Reiki, Aromatherapy and Emotional Freedom Technique. Each case has resulted with a positive lifestyle change, promotion of self-love and worth, reduction in physical, mental and spiritual damage of where 95% healing has been seen within a year with longevity and adherence. It is seen that the Quantum Medicinal Approach to Life Coaching and Energy Work facilitates the healing of these women affected by abusive narcissistic relationships.
Egalet Corporation Wayne, USA
Keynote: Importance of “level of effort” in the evaluation of abuse-deterrent drugs – the multi-faceted approach to the fight against opioid abuse – what can, and can’t we expect from ADFs
Time : 10:50-11:35
Karsten Lindhardt has been the initiator of the CCALC Cat 1 focus group, which purpose has been to make meetings for professionals in the abuse deterrence space with a particular interest in the field of in vitro abuse deterrence studies. Dr Lindhardt is the CSO of Egalet Corp. and has 20 years of experience as a scientific manager in the pharmaceutical industry. Dr Lindhardt has earned a Diploma of Business Excellence (DBE) at Columbia University, Copenhagen Business School. Dr Lindhardt received an MSc in Pharmaceutics and a Ph.D. in pharmaceutical development and pharmacology, each from the Royal Danish School of Pharmacy, Copenhagen DK.
Statement of the Problem: The effort expended in attempts to manipulate a prescription opioid is an important element of Category 1, 2 and 3 studies of AD (abuse-deterrent) opioids, but it is challenging to assess this objectively. Epidemiologic data indicate that making the manipulation of opioid drugs more challenging (‘more effort’) creates new community dynamics, reducing the misuse/abuse of AD opioids. Pinney Associates (Bethesda, MD) has developed the ALERRTTM instrument for ‘level of effort’ evaluations. Egalet has worked with Pinney Associates on creating data on a morphine ER product developed with AD properties (ARYMO® ER; Egalet US Inc., Wayne, PA) was assessed with Egalet’s proprietary ADF technology using the ALERRT instrument as part of the evaluation of its abuse-deterrent formulations (ADFs) has shown that making the manipulation of the opioid drugs more challenging taking “more effort” to create an effective abusable form of the drug creates new dynamics in the abuser communities. The purpose of the study discussed herein was to describe the experience with the ALERRT tool in the evaluation of ARYMO® ER and how these data are important in the holistic evaluation of the abuse-deterrent properties of a drug.
Findings: A significantly higher level of effort was needed to manipulate ARYMO® ER tablets relative to the non-abuse deterrent comparator across the 10 tools that were tested. The expectation is that making opioid drug products more difficult to misuse/ abuse will, in time, be a barrier to misuse/abuse for opioid naïve patients rather than preventing experienced opioid abusers from indulging in addictive behavior.
Conclusion & Significance: Tools are available for evaluation of ‘level of effort’ and can provide relevant and important data for characterization of abuse-deterrent properties. ARYMO® ER was shown to be very resistant to manipulation. It is believed that a multifaceted approach to combat the abuse is needed and AD opioids, in concert with several other critical initiatives.
Confidential Recovery, USA
Time : 11:35-12:20
Scott H Silverman is a Crisis Coach, behavioral health advisor, and leads the team at Confidential Recovery—an intensive substance abuse recovery program for adults, 18 years old. As the author of Tell Me No, I Dare You: A Guide for Living a Heroic Life, Scott shares strategies for living an authentic and fulfilling life. Scott has received numerous awards and honors including being named CNN Hero of the Week and the City of San Diego honored him by selecting February 19 as “Scott Silverman Day” for his contributions to the community. As the Founder of Second Chance, Scott worked to break the cycle of substance abuse, unemployment, poverty, and homelessness. For over 15 years, Scott assisted more than 25,000 people in San Diego with job readiness training, employment placement assistance, mental health counseling, case management, and affordable housing referrals to people who desire to change their lives.
Confidential Recovery was founded five years ago as an alternative to the current abstinence model of treatment that was based on an 80-year-old philosophy. While effective for its time in treating addiction, it did not transfer well to poly users. This was also buttressed by studies that demonstrated that detox and residential treatment programs alone, still yielded a 95% rate of relapse. We knew we needed to change the paradigm. Our core beliefs were built around harm-reduction to ease clients’ transition into sobriety. Methadone and suboxone were currently and commonly in use for certain parts of the SUD population. We were challenged by a number of issues we had not anticipated: (a) Fellow treatment providers were strongly wedded to the total abstinence model and were reluctant to make referrals to us. (b) Identifying physicians and psychiatrists who supported the benefit of medication assisted treatment that supported the non-biological aspects of SUD. In other words, they viewed their medical support as a companion to a psychosocial treatment approach. (c) Identifying SUD treatment providers who believed in the integrative approach of medicine evidenced-based treatment to aid in the physical transition to sobriety. (d) There were no pre-existing adaptive models of medically assisted treatment(MAT) that existed and were readily available at the time. Integrating all of these have allowed us to create what we believe to be a replicable model that we can share with others wishing to make the transition from abstinence-based treatment to harm reduction, medically assisted treatment.
Special Pain Therapy Clinical Geriatrics, Germany
Time : 12:20-13:05
Roland Worz is experienced with pain patients as a psychiatrist and neurologist since the 1970s. He owns a Master degree in Medicine Ethics. From 1975 to 1984, he was secretary of the German-speaking chapter of the International Association for the Study of Pain (IASP). He published over 200 scientific papers on pain and brought out ten books on this topic, especially dealing with abuse, dependence, and addiction to pain patients. A personal approach using complexity theory is needed to overcome the limitations of narrow nociceptive/neuropathic pain concepts and provide greater consideration of the person. His goal is to avoid damages of opioid overuse by applying adequate personal treatment with appropriate assessment, history, and regular controls of chronic pain patients, as well as by considering ethical values.
Both NSAIDs and opioids are valuable substances in the treatment of acute pain. However, their prolonged administration, extending over a few weeks implies the risk of severe complications. In the case of acute pain, the model of nociception is usually used in assessment, explanation, and therapy. In contrast, chronic pain is only in a part of the cases result of injury or surgery. Therefore, the established definition of chronic pain as “any pain that persists beyond the anticipated time of healing” is misleading. It is suggesting the existence of nociceptive, neuroplastic, and neoplastic mechanisms with the consequence of analgesic drug administration. In the majority of chronic pain syndromes, there is a multifactorial etiopathogenesis with biological, psychological, and social influences. For such patients, the complexity theory might be a more appropriate conceptual framework than conventional, sequential models of nociception. In the case of simple pain states, the link between stimulus and pain experience is linear, whereas in complex pain conditions there are multiple associations among elements, between which there may be nonlinear and nondeterministic relations. The terms causal sequence and network illustrate the fundamental differences. In addition, clinical pain is often the result of multiple chronification factors, which contribute to complexity. The origin and development of analgesic drug abuse are multifactorial and complex, too. In the case of chronic pain, there are often associations with depressive disorders, different anxiety syndromes, posttraumatic stress disorder, and other psychiatric conditions. In all these disorders, pain experiences may be components of the disease. Complexities can be analyzed and controlled. In the case of chronic pain, the stimulus-response-scheme pain-analgesic drug administration is not appropriate and often dangerous. Prolonged use of analgesic drugs is only appropriate in exceptions. If necessary, a systematic, patient-centered management with regular controls is adequate. The assessment of biography, psychological features and functioning in family and profession is useful. The dangers of addiction, diversion, abuse, and misuse should be carefully observed in regular therapeutic intervals. Prevention is better than cure!