Steven Crain
Pondera Pharmaceuticals, USA
Biography
Steven Crain completed his Ph.D. in Clinical Psychology from Duke University in 1980. Since then he has treated thousands of patients with addictions, anxiety,
and depression as Clinical Director of Penn State University’s Center for Counseling and Psychological Services and at Therapeutic Alliance, a community-based
mental health center he established in 1982. In 2009, Dr. Crain co-founded Pondera Pharmaceuticals, Inc. a company dedicated to the development and marketing
of pharmaceuticals and nutraceuticals for the treatment of addictions, anxiety, and depression. Dr. Crain has co-authored several articles, which summarize their
research and innovative treatments, and has been awarded several patents.
Matthew Crain is completing his honors thesis in Biology at Duke University on the “Impact of early life stress on neural network dysregulation and depression.”
He has been a research assistant at Pondera Pharmaceuticals, Inc. since 2009 where he has collaborated on research on innovative methods to treat anxiety,
depression, and addictions. He is co-author of a 2013 JBBS paper on “Emotional and physical distress relief using a novel endorphinergic formulation.”
Stanley M. Crain completed his Ph.D. in Biophysics from Columbia University in 1954. Dr. Crain is a world-renowned expert in opioid addiction with over 100
publications cited in PubMed and numerous honors and awards. Dr. Crain’s 30+ years of preclinical electrophysiological nerve tissue culture studies led to his
discovery of the imbalances in the endogenous opioid system created by exposure to opioid drugs, which are responsible for the development of tolerance and
dependence. Dr. Crain’s research also led to the discovery of simple methods to restore balance to the endogenous opioid system, thereby reducing tolerance
and dependence. Dr. Crain has been awarded numerous patents. Pain Therapeutics, Inc. and Pondera Pharmaceuticals, Inc. were both founded to translate Dr.
Crain’s groundbreaking discoveries into safe and effective treatments for addictions and anxiety.