4^th International Conference and Exhibition on Addiction Research and Therapy August 03-05, 2015 Orlando, Florida, USA

Dr. Soumya Sachdeva has completed her MBBS (Bachelors of Medicine and Surgery) at the age of 24 years from Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India . She is very passionate about medical research and has 5 publication in Pubmed and 2 others in peer reviewed journals. She also is the editor board of Journal of Young Medical Researchers, wikidoc.org and is also the Ambassdor for International Journal of Medical Students (IJMS).

Abstract: Substance abuse has been defined as the use of chemical substances for non medical purposes in order to achieve alterations in psychological functioning. The substances commonly abused in India include alcohol, cannabis and opioids. However the use of solvents and propellants is also on the rise as these are inexpensive, legally available household, industrial, office and automobile products; which is more commonly seen in children and adolescents. We hereby describe a 16 year old boy with combined volatile and alcohol abuse. During the phase of acute alcohol intoxication alone; the adolescent complained of nausea, headaches, dizziness and excessive somnolence however when combined with glue sniffing; disorientation and ataxia, restless, diaphoresis and nystagmus were complained of, in addition. The child also developed blurring of vision and inability to perceive numbers and letters in the central visual field and fixed hearing deficits to increased frequency sound was noted; more prominent during the last 2 months, during which period combined abuse was done and dose of alcohol was increased to about 14- 16 drinks per week. A progressively increasing tendency of violence, disorientation, restlessness was noticed by the mother and his family in the form of anger outbursts, abusive and assaultive behavior in the last two months during which alcohol intake was accelerated. During the phase of abstinence; the child complained of increasing slurring of speech, difficulty hearing voices and sleep disturbances. The contrast study of the head showed mild cortical and cerebellar atrophy with slight attenuation of white matter and cortical atrophy was more pronounced over left temporal lobe. The patient presented to outpatient with the features of withdrawal ; pharmacological therapy was begun using thiamine ,benzodiazepines were given to decrease agitation, and maintenance fluids were begun as well ,buspirone was begun as 5 mg/day and increased to 30mg/day when the child became stabilized, cognitive behavioural therapy followed by supportive psychotherapy and family based approach and person centered general counseling was adopted when the condition of the child stabilized .This case is first of the kind depicting clinical features as well as withdrawal of combined volatile and moderate alcohol abuse. This case report also sensitizes the practitioners to increasing prevalence of combined alcohol and volatile substance abuse and growing problem of the same.

She is Associate Professor at Department of Public Health at China Medical University. She has done her Bachelor of Science in China Medical University and afterwards her Masters from Yang Ming University. Later, she moved to Los Angeles School of Public Health at University of California, USA. She has research specialty with Social Epidemiology, Health behaviors, Health education, Health promotion and Health Psychology.

Background & Aim: Many studies revealed the association between mental illness (MI) and substance-related disorders (SRD) but little is known about the temporal relationship on this association. Therefore, the purpose of this study was to examine whether individuals with mental illness would have a higher risk of subsequentonset of substance-related disorders compared to those without mental illness.rnrnMethods: A retrospective cohort study was conducted by using the nationwide population-based Taiwan National Health Insurance Research Dataset (NHIRD) consisting of 2,000,000 patients’ records from 2000 to 2009. We observed two study cohorts. The case cohort was patients diagnosed with ICD-9-CM codes 296.xx, 300.xx, 301.xx since January 1, 2001 to December 31, 2006. The control cohort was simultaneously and randomly selected from those without the diagnosed codes with matching age, gender, income and urban levels. A total of 124,423 case and the same size of control cohorts were followed up to see the subsequent onset of SRD (diagnosed codes 291-292, 303-305), till the end of 2009. Cox Proportional Regression Models were used. rnrnResults: The risk of subsequently developing SRD in patients with MI is about 5 times (HR=5.09, 95% CI: 4.74-5.48) higher than those without, with controlling for age, gender, urban and income levels. After using cox regression models for analyzing stratified sub-samples by age strata, gender, urban levels, and income levels, we found in all results of the subsamples, the hazard ratios of the onset of SRD between cases and controls were all significantly higher than 1.0 (hazard ratios with 95% CI ranged from 2.12 (1.65-2.87) to 14.55 (7.89-26.83). Among the results, age drew a lot of attentions because the onset of mental illness for youngsters aged 10 to 19 years could increase 14.55-fold risk for them to develop SRD in their later life. And the hazard ratio increased with declining age. rnrnConclusions: The results in our study suggested that the onset of mental illness in people’s earlier life did have a potential risk for them to develop substance-related disorders in later life. Therefore, health professionals for developing prevention programs on substance use and abuse should pay more concerns on the population at risk, especially on adolescents or young adults with mental illness; and practitioners in clinical settings should adopt more comprehensive approaches in the treatment of substance-related disorders with taking psychiatric disorders into accounts. rn